Description

The response of a patient with Langerhans Cell Histiocytosis (LCH) to therapy can be classified into semi-quantitative categories (LCH III).


Patient selection: Langerhans Cell Histiocytosis ay 6 weeks after therapy

 

General Category

Response

Alternative

better

complete resolution

non-active

better

regression

active disease-better

interrmediate

mixed

active-mixed

intermediate

stable

active-unchanged

worse

worse

active disease-worse

 

Mixed: regression in one site AND progression in another

 

Stable: neither regression nor progression

 

Worse: progression of signs and symptoms and/or appearance of new lesions

 

Existing Lesions

New Lesions

Signs and Symptoms

Response

inactive

none

none

non-active

regression

none

better

active-better

regression

present

unchanged

active-mixed

unchanged

none

unchanged

active-unchanged

progression

NA

progression

active-worse

unchanged

present

progression

active-worse

 


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