Ward and Gibb listed criteria for probable Parkinson's Disease suitable for research. The authors are from Southampton General Hospital in England.


Criteria - all of the following:

(1) The presence of a disorder that is progressive in its clinical course.

(2) The presence of 2 or 3 of the following cardinal features:

(2a) bradykinesia

(2b) rigidity

(2c) tremor

(3) The presence of >= 2 of the following findings:

(3a) asymmetry at onset

(3b) asymmetry of signs

(3c) tremor as the initial symptom

(3d) marked response to levodopa, with either functional improvement and/or dyskinesia

(4) Exclusion: The absence clinical findings characteristic for an alternative diagnosis.

(5) Exclusion: The absence of a disorder known to cause similar clinical findings.


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