Hydrogen peroxide (H2O2) decomposes into oxygen and water. The release of oxygen can cause adverse effects when it occurs in a closed space.
The volume of oxygen released depends on the concentration and volume of the hydrogen peroxide used.
1 mL of Peroxide Solution |
Volume Oxygen Released |
2.5% |
8 mL |
3.0% |
10 mL |
3.5% |
12 mL |
30% |
100 mL |
mL of oxygen released =
= (percent oxygen as a number from 0 to 100) * 3.33 * (mL hydrogen peroxide)
Exposures can be by:
(1) swallowing
(2) enema
(3) bowel irrigation
(4) wound or abscess irrigation
Effects:
(1) gastric distention with belching
(2) bowel distention with perforation
(3) arterial gas embolism, which can result in stroke
(4) venous gas embolism, which can accumulate in the right ventricle with marked decrease in cardiac output
(5) intravascular foaming
(6) soft tissue emphysema
Specialty: Toxicology, Emergency Medicine, Critical Care