Arnaud et al reported a disease activity index (RPDAI) for a patient with relapsing polychondritis. This can help to monitor the course of the disease and its response to therapy. The authors are from multiple institutions from around the world.
Patient selection: relapsing polychondritis
Finding
Weight
arthritis
1
fever
2
purpura
3
elevated serum CRP
3
manubriosternal chondritis
3
sternoclavicular bursitis
4
hematuria
4
costochondritis
4
episcleritis
5
proteinuria
6
vestibular dysfunction
8
nasal chondritis
9
pericarditis
9
uveitis
9
auricular chondritis
9
scleritis
9
corneal ulcer
11
motor or sensorineural neuropathy
12
sensorineural deafness
12
retinal vasculitis
14
respiratory chondritis without acute respiratory failure
14
medium and/or large vessel vasculitis
16
myocarditis
17
renal failure
17
acute aortic or mitral valve insufficiency
18
encephalitis
22
respiratory chondritis with acute respiratory failure
24
disease activity index =
= SUM(weights for all of the items present)
Interpretation"
• minimum score: 0
• maximum score: 251
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