Description

Arnaud et al reported a disease activity index (RPDAI) for a patient with relapsing polychondritis. This can help to monitor the course of the disease and its response to therapy. The authors are from multiple institutions from around the world.


Patient selection: relapsing polychondritis

 

Finding

Weight

arthritis

1

fever

2

purpura

3

elevated serum CRP

3

manubriosternal chondritis

3

sternoclavicular bursitis

4

hematuria

4

costochondritis

4

episcleritis

5

proteinuria

6

vestibular dysfunction

8

nasal chondritis

9

pericarditis

9

uveitis

9

auricular chondritis

9

scleritis

9

corneal ulcer

11

motor or sensorineural neuropathy

12

sensorineural deafness

12

retinal vasculitis

14

respiratory chondritis without acute respiratory failure

14

medium and/or large vessel vasculitis

16

myocarditis

17

renal failure

17

acute aortic or mitral valve insufficiency

18

encephalitis

22

respiratory chondritis with acute respiratory failure

24

 

disease activity index =

= SUM(weights for all of the items present)

 

Interpretation"

• minimum score: 0

• maximum score: 251


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