Relapsing Polychondritis Damage Index (RPDAM) of Mertz et al

Description

Mertz et al reported the Relapsing Polychondritis Damage Index (RPDAM) as a disease-specific damage score. This can help to monitor the patient and the response to therapy. The authors are from multiple institutions from around the world.

Domains:

(1) ear

(2) nose

(3) eye

(4) respiratory tract

(5) cardiovascular

(6) hematological

(7) treatment related

Damage was defined as an irreversible disease manifestation that is unlikely to benefit from disease escalation AND present for >= 3 months.

The onset of damage should be after the diagnosis of onset of relapsing polychondritis.

Domain	Damage Item
ear	permanent auricular cartilage deformities
	sensorineural hearing loss
	conductive hearing loss
	permanent vestibular syndrome
nose	nasal bridge collapse or septal perforation
eye	scleromalacia (scleral thinning)
	blindness in one or both eyes
	orbital wall destruction
respiratory tract	permanent chest wall deformities
	dysponia
	obstructive syndrome (laryngeal, tracheal, bronchial)
cardiovascular	aortic root dilatation
	left ventricular dysfunction
	major tissue loss
hematological	myelodysplasia with transfusion dependency
treatment-related	osteoporosis with fractures or vertebral collapse
	avascular necrosis

damage index =

= SUM(number of items present)

Interpretation:

• minimum index: 0

• maximum index: 17

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Relapsing Polychondritis Damage Index (RPDAM) of Mertz et al

Description

Specialty