Description

Scott et al used recursive partitioning analysis (RPA) to evaluate a patient >= 70 years old with glioblastoma multiforme. This can help to identify a patient who may benefit from more aggressive management. The authors are from multiple hospitals in the United States and France.


 

Patient selection: glioblastoma multiforme and age >= 70 years

 

Outcome: median survival

 

Parameters:

(1) surgical procedure

(2) age of the patient in years

(3) Karnofsky performance status (KPS)

Surgery

Age in Years

KPS

Median Survival

biopsy

NA

70 to 100

4.3-4.6 months

biopsy

NA

< 70

2.3-3.1 months

resection (gross total, partial)

< 75.5 years

NA

8.5-9.3 months

resection (gross total, partial)

>= 75.5 years

NA

6.4-7.7 months

 

where:

• The range comes from data at Memorial Sloan Kettering Cancer Center and the French data set.

 


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