Description

The 2005 consensus conference for the International Society of Urological Pathology (ISUP) recommended that the Gleason score be modified when a tertiary pattern is present.


 

If 3 patterns are identified in a biopsy:

(1) the first component of the Gleason score is the most prevalent pattern

(2) the second component is the higher of the 2 remaining grades, irrespective of the amount present

 

Patel et al demonstrated that a patient with patterns 3 and 4 and with a tertiary pattern 5 behaved worse than a patient with a score of 7.

 


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