Description

Augustine et al developed a clinical score for identifying a patient with a bloodstream infection caused by an extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBLE). This score can help decide whether or not a carbapenem should be started before susceptibility results are available. The authors are from the University of South Carolina.


Patient selection: bloodstream infection (BSI) with monomicrobial isolate of an Enterobacteriaceae

 

Decision: use of carbapenem because of extended-spectrum beta-lactamase production

 

Parameters:

(1) ESBL prediction score of Augustine et al (range from 0 to 8)

(2) Pitt Bacteremia Score of Paterson et al (range from 0 to 14)

 

ESBL PS

Pitt Bacteremia Score

Decision for Carbapenem

0

NA

no need

1 or 2

< 4

no need

1 or 2

>= 4

consider

3 or more

NA

start

 


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