chronic lung disease with emphysematous areas and thickened interstitium (fibrosis and hypertrophied peribronchial muscle)
IV
Limitations (Edwards):
• The original sequence of progression through 4 stages is rarely seen today due to changes in management and ventilatory support. Stages II and III are infrequent, and the final end-stage has a more homogeneous appearance with less hyperexpansion.
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