Radiation to the abdomen and pelvis may result in intestinal injury. Certain factors can increase the risk of intestinal injury.
previous abdominal or pelvic surgery
adhesions and scarring limit the mobility of the intestine, making it more likely that a beam will affect a limited portion of the intestine
diabetes mellitus, hypertension, atherosclerosis, cardiovascular disease
vascular occlusive disease
thin, elderly and female
more small intestine within radiation field
chemotherapy during or immediately after the radiation therapy
increased radiation sensitivity
increasing dose of radiation
The risk of injury increases with:
(1) the severity of any one underlying risk factor
(2) the number of risk factors present
I would think malnutrition and other factors reducing the healing process would also favor injury.
To read more or access our algorithms and calculators, please log in or register.
Purpose: To identify a patient at risk for intestinal injury following abdominal or pelvic radiation therapy.
Specialty: Hematology Oncology, Gastroenterology
Objective: risk factors, adverse effects