Ferrari et al reported the Quick Acute Kidney Injury (q-AKI) score for predicting acute kidney injury in patients in a multidisciplinary intensive care unit (ICU). The authors are from multiple institutions in Europe and South America.
Patient selection: admission to a multidisciplinary intensive care unit
Outcome: development of acute kidney injury (AKI) within the first week of ICU stay
Parameters:
(1) obesity (BMI > 30 kg per square meter)
(2) admission eGFR in mL per min per 1.73 square meters
(3) SOFA cardiovascular subscore, from 0 to 4
(4) serum lactate in mmol/L
(5) TIMP-2 (tissue inhibitor of metalloproteinases 2)
(6) IGFBP7 (insulin-like growth factor-binding protein 7)
Parameter
Finding
Points
obesity
non-obese (absent)
0
obese
1
eGFR
>= 90
0
< 90
3
SOFA cardiovascular
0 or 1
0
>= 2
2
serum lactate
< 2 mmol/L
0
>= 2 mmol/L
2
(TIMP-2)*(IGFBP7)
< 0.3 ((ng/mL)^2/1000)
0
>= 0.3 ((ng/mL)^2/1000)
2
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 10
• The higher the score the greater the risk of developing AKI.
Total Score
Percent AKI
<= 2
14-20%
3 or 4
21-22%
5 or 6
34-43%
7 or 8
56-57%
>= 9
69-77%
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