PUV Risk Score of Coleman et al

Description

Coleman et al reported the PUV risk score for evaluating a child with a neonatally diagnosed posterior urthral valve (PUV). This can help to identify a child who is at increased risk for renal failure. The authors are from Birmingham Children’s Hospital in Birmingham, England.

Patient selection: child with a posterior urethral valve diagnosed when a neonate

Outcome: chronic renal impairment

Parameters:

(1) nadir serum creatinine in µmol/L during the first year after diagnosis

(2) creatinine velocity in µmol/L/day (slope of serum creatinine over the 5 days after initial bladder drainage)

Parameter	Finding	Points
nadir serum creatinine	< 35 µmol/L	1
	35 to 75 µmol/L	2
	> 75 µmol/L	3
creatinine velocity	< - 3 µmol/L/day	1
	-3 to 3 µmol/L/day	2
	> 3 µmol/L/day	3

PUV risk score =

= SUM(points for both parameter)

Interpretation:

• minimum PUV risk score: 2

• maximum PUV risk score: 6

• The higher the PUV risk score the greater the risk of renal impairment.

PUV Risk Score	Chronic Renal Impairment
2	0%
3	8%
4	50%
5	64%
6	100%

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