Variation in pulse pressure and systolic blood pressure can be predictive of a response to a fluid challenge.
Parameters:
(1) maximum pulse pressure in mm Hg over 1 minute
(2) minimum pulse pressure in mm Hg over 1 minute
(3) maximum systolic blood pressure in mm Hg over 1 minute
(4) minimum systolic blood pressure in mm Hg over 1 minute
pulse pressure =
= (systolic systemic arterial pressure) - (diastolic systemic arterial pressure)
percent pulse pressure variation =
= ((maximum pulse pressure) - (minimum pulse pressure) / (0.5 * ((maximum pulse pressure) + (minimum pulse pressure))) * 100%
percent systolic pressure variation =
= ((maximum systolic pressure) - (minimum systolic pressure) / (0.5 * ((maximum systolic pressure) + (minimum systolic pressure))) * 100%
Interpretation:
• A pulse pressure variation >= 11% is associated with being a fluid responder (increase in cardiac output after 500 mL fluid challenge) during mechanical ventilation after CABG surgery.
