A patient with Marfan's syndrome may have one or more psychiatric problems. It may be difficult to determine whether this is a coincidental finding or related to the underlying hereditary disorder.


Psychiatric problems seen in Marfan's syndrome include:

(1) generalized anxiety

(2) depression

(3) schizophrenia

(4) other psychosis

(5) cognitive impairment


Some patients may have evidence of cerebrovascular injury secondary to vascular changes on imaging studies (Lee et al, 2013).


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