Metastatic carcinoma to the eye may cause changes resembling a hypopyon.
The metastatic focus is located in the uvea (iris, ciliary body).
Tumors that have metastasized to this region include:
(1) retinoblastoma
(2) lung cancer
(3) squamous cell carcinoma of the esophagus
The presentation is variable and may include:
(1) conjunctivitis
(2) material in the dependent anterior chamber
(3) elevated intra-ocular pressure
(4) ocular pain
(5) hyphema
The diagnosis can be challenging, especially if the patient is not known to have cancer.