Melanosis of the prostate is a rare condition.
Prostate tissue is grossly black or dark in color.
Histologic features:
(1) melanin pigment in glandular epithelium
(2) melanin pigment in the stroma
(3) absence of melanocytic proliferation
(4) benign histology
Concurrent prostatic hypertrophy or adenocarcinoma may be present.
Differential diagnosis:
(1) blue nevus of the prostate
(2) malignant melanoma
(3) hemosiderosis or hemochromatosis
