Duflos et al reported the proSCANNED score for predicting mortality for a patient with heart failure. The authors are from Universite Montpellier and associated hospitals in France.
Patient selection: stable heart failure
proSCANNED is an acronym derived from the various parameters.
Parameters:
(1) age in years (A)
(2) NYHA class (N)
(3) left ventricular ejection fraction (LVEF) in percent (E)
(4) serum NT-proBNP in pg/mL ("pro")
(5) beta-blocker therapy (N)
(6) diabetes (D)
(7) COPD (C)
(8) current smoker (S)
Parameter
Finding
Points
age in years
< 75 years
0
>= 75 years
1
NYHA class
NYHA 1 or 2
0
NYHA 3 or 4
1
LVEF
> 35%
0
<= 35%
1
NT-proBNP
<= 5,000 pg/mL
0
> 5,000 pg/mL
1
beta-blocker therapy
no
1
yes
0
diabetes
no
0
yes
1
COPD
no
0
yes
1
current smoker
no
0
yes
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 8
• The risk of mortality at 1 and 4.4 years increases as the score increases.
• The risk is low for a score of 0 or 1.
• The risk of dying increases exponentially from scores of 4 and higher.
Performance:
• The area under the ROC curve is 0.79 in the derivation and 0.71 in the validation cohorts.
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