Propranolol therapy can improve the appearance of cutaneous hemangiomas. It may also be helpful in treating other types of hemangiomas.
Patient selection: Therapy is usually considered for large or disfiguring hemangiomas.
Drug: propranolol hydrochloride
Dose: 2 mg per kg per day (up to 3 mg per kg per day) po
Duration of therapy: 24 weeks or more
(1) episodes of hypotension, bradycardia or hypoglycemia are uncommon
(2) some patients may have agitated sleep (Bagazgoitia et al)
(1) a moderate decrease in volume of the hemangioma
(2) some decrease in redness and elevation
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Specialty: Cardiology, Genetics, Pedatrics