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Prophylactic Measures to Prevent Infection in Patients with Sickle Cell Disease

Specialty:

Infectious Diseases
Clinical Pharmacology
Hematology Oncology
Genetics

Objective:

ICD-10:

Description:

Bacterial infection is a major cause of morbidity and mortality in patients with sickle cell disease. Loss of splenic function is an important risk factor, increasing the susceptibility to encapsulated organisms. A prophylactic strategy using both vaccinations and antibiotic therapy can significantly reduce the risk of infection, especially in children.

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