An alcoholic may experience a prolongation of the QTc interval. Prolongation of the QTc interval may be associated with sudden death.
Patient selection: alcoholic on 30th day of abstinence
Parameters:
(1) QTc interval in msec
(2) coefficient of variation of the R-R interval (CVRR)
Autonomic dysfunction was present if the CVRR < 80^ of predicted.
Risk factors for prolongation of the QTc compared to normal controls:
(1) alcoholic
(2) autonomic dysfunction
The risk can be further increased by drugs or comorbid conditions that can increase the QTc.
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Specialty: Cardiology, Toxicology