Lyth et al developed a prognostic subclassification for T1 cutaneous malignant melanomas. This can help to identify a patient who may benefit from more aggressive management. The authors are from multiple universities in Sweden.
Patient selection: T1 cutaneous melanoma
Parameters:
(1) ulceration
(2) thickness in millimeters
(3) Clark level (from II to V)
Ulceration
Thickness
Clark Level
Risk Group
no
<= 0.75 mm
II or III
low
no
> 0.75 mm
II or III
intermediate
no
NA
IV or V
intermediate
yes
<= 0.75 mm
II
intermediate
yes
> 0.75 mm
II
high
yes
NA
III, IV or V
high
Risk Group
10-Year Cumulative Mortality
low
1.5%
intermediate
6%
high
16%
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