Prognostic Scores of Feldman et al for Men with Germ Cell Tumor Metastatic to the Brain: Score for Brain Metastasis Present at the Time of Initial Presentation

Description

Feldman et al reported prognostic scores for men with germ cell tumors (GCT). One score was for patients with brain metastases detected at the time of initial diagnosis (referred to as synchronous). The authors are from multiple institutions in Europe and North America.

Patient selection: male with brain metastases present at the time of initial diagnosis

Parameters:

(1) number of brain metastases

(2) metastases to liver and/or bone

(3) primary site

Parameter	Finding	Points
number of brain metastases	1	0
	2 or more	1
metastases to bone and/or liver	no (no metastases to either)	0
	yes (metastases to one or both)	1
primary site	testis or retroperitoneum	0
	mediastinum or other	1

total score =

= SUM(points for all 3 parameters)

Interpretation:

• minimum score: 0

• maximum score: 3

• The higher the score the worse the overall prognosis.

Score	Risk	5 Year Survival
0	low	64%
1	intermediae	52%
2	high	25%
3	very high	0%

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Prognostic Scores of Feldman et al for Men with Germ Cell Tumor Metastatic to the Brain: Score for Brain Metastasis Present at the Time of Initial Presentation

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