Van Koningsveld et al reported a clinical prognostic score for a patient with Guillain-Barre syndrome. This can help to identify a patient who is at risk for prolonged disability. The authors are from Erasmus MC Rotterdam and King's College London.
Patient selection: Guillain-Barre syndrome
Outcome: inability to walk independently at 6 months
Parameters:
(1) age at onset in years
(2) diarrhea preceding onset (<= 4 weeks)
(3) GBS disability score of Hughes, from 0 to 6
Parameter
Finding
Points
age at onset
<= 40 years
0
41 to 60 years
0.5
> 60 years
1
diarrhea
no
0
yes
1
GBS disability
0 or 1
1
2
2
3
3
4
4
5
5
score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 1
• maximum score: 7
• The higher the score the greater the risk of not being able to walk at 6 months.
Score
Percent Unable to Walk
1
1%
2
2.4%
3
3.6%
4
8.4%
5
25%
6
57%
7
83%
Performance:
• The area under the ROC curve is 0.85.
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