Prognostic Score of Sampaio et al for Mortality in a Pediatric Patient with Visceral Leishmaniasis

Description

Sampaio et al reported a simple score for identifying a pediatric patient with visceral leishmaniasis who is at increased risk of mortality. This can help to identify a patient who may require more aggressive management. The authors are from Universidade Federal de Pernambuco and affiliated institutions in Recife, Brazil.

Patient selection: pediatric patient < 15 years old with visceral leishmaniasis

Case fatality rate in study: 10%

Parameters:

(1) dyspnea

(2) associated bacterial infection (pneumonia, gastroenteritis, sepsis, otitis media, skin abscess)

(3) absolute neutrophil count per microliter

(4) jaundice

(5) mucosal bleeding

(6) platelet count per microliter

Parameter	Finding	Points
dyspnea	no	0
	yes	1
bacterial infections	no	0
	yes	1
absolute neutrophil count	>= 500 per µL	0
	< 500 per µL	1
jaundice	no	0
	yes	2
mucosal bleeding	no	0
	yes	2
platelet count	>= 50,000 per µL	0
	< 50,000 per µL	3

total score =

= SUM(points for all of the parameters)

Interpretation:

• minimum score: 0

• maximum score: 10

• A score >= 3 was associated with increased risk of mortality.

Performance:

• The area under the ROC curve is 0.895 with sensitivity 0.89 and specificity 0.79.

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Prognostic Score of Sampaio et al for Mortality in a Pediatric Patient with Visceral Leishmaniasis

Description

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