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Prognostic Score of Nordlinger et al for Patients with Surgical Resection of Metastatic Colorectal Carcinoma to the Liver

Purpose: To evaluate a patient after resection of hepatic metastases from a colon carcinoma using the prognostic score of Nordlinger et al.

Description

Nordlinger et al developed a prognostic score for predicting survival of patients after resection of metatastic lesions to the liver from a colorectal adenocarcinoma. This can help advise patients prior to surgery and identify patients most likely to benefit from the surgery. The authors are from Hopital Saint Antoine in Paris and Hopital de Hautepierre in Strasbourg.


Parameters:

(1) age of the patient

(2) size of largest metastasis

(3) extension into the serosa of the primary carcinoma

(4) lymphatic spread of the primary carcinoma

(5) disease free interval

(6) number of liver nodules

(7) resection margins

 

Parameter

Finding

Points

age of the patient

<= 60 years

0

 

> 60 years

1

size of the largest metastatic nodule

<= 5 cm

0

 

> 5 cm

1

extension into the serosa in the primary

absent

0

 

present

1

lymphatic spread in the primary

absent

0

 

present

1

disease free interval

>= 2 years

0

 

< 2 years

1

number of liver nodules

< 4

0

 

>= 4

1

resection margin

>= 1 cm

0

 

< 1 cm

1

 

number of risk factors =

= SUM(points for all 7 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 7

• The higher the score, the worse the prognosis.

 

Number of Risk Factors

2 Year Survival Rate

0 – 2

79%

3 – 4

60%

5 - 7

43%

 


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Specialty

Objective

ICD-10