Liu et al reported a new prognostic score for a patient with newly diagnosed primary CNS lymphoma. The authors are from multiple institutions in Taiwan and England.
Parameters:
(1) age in years
(2) deep brain lesions
(3) ECOG status
Parameter
Finding
Points
age in years
< 80 years
0
>= 80 years
1
deep brain lesions
no
0
yes
1
ECOG status
0 or 1
0
2 to 4
1
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
• The higher the score the worse the outcome.
Score
Risk Group
Progression-Free Survival
0
low
3.9 years
1
intermediate
1.7 years
2
high
0.7 years
3
very high
0.1 years
Performance:
• The area under the ROC curve is 0.67.
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