Description

Gonzalez-Medina et al reported a prognostic score for evaluating patients with chronic myelomonocytic leukemia (CMML). The authors are from Hospital General Vail d;Hebron in Barcelona.


Patient selection: chronic myelomonocytic leukemia (CMML)

 

Parameters:

(1) serum LDH in U/L

(2) percent blasts in the bone marrow

(3) white blood cell count in 10^9/L

 

Parameter

Finding

Points

serum LDH

<= 1.5 times ULN

0

 

> 1.5 times ULN

1

percent blasts bone marrow

<= 5%

0

 

> 5%

1

WBC count

<= 10 * 10^9/L

0

 

> 10 * 10^9/L

1

 

total score =

= SUM(points for all 3 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 3

 

Score

Risk Group

Median Survival

0 or 1

low

44 months

2 or 3

high

7 months

 


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