Description

Ghobrial et al developed a simple prognostic score for evaluating an adult with a solid organ transplant who develops a post-transplantation lymphoproliferative disorder (PTLD). This can help identify patients who may benefit from more aggressive management. The authors are from the Mayo Clinic.


Parameters:

(1) ECOG performance status

(2) involvement of the transplanted organ by the PTLD

(3) tumor pattern

 

Parameter

Finding

Points

ECOG performance

0, 1 or 2

0

 

3 or 4

1

transplanted organ

not involved by the PTLD

0

 

involved by the PTLD

1

tumor pattern

monomorphic

1

 

polymorphic

0

 

total score =

= SUM(points for all 3 parameters)

 

Interpretation:

• minimum score: 0

• maximum score: 3

 

Total Score

Probability of 5 Year Survival

Median Survival

0 or 1

60%

89 months

2

16%

3 months

3

0%

1 month

from Figures 1 and 2, page 7579


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