Chen et al reported a prognostic score for a patient with nasopharyngeal cancer and bone metastases. This can help to identify a patient who may require more aggressive management. The authors are from multiple institutions in China.
Patient selection: nasopharyngeal cancer with bone metastases
Parameters:
(1) age in years
(2) anemia
(3) N stage
(4) bone metastasis free interval in months (time from initial diagnosis to first bone metastasis)
(5) radiation therapy to primary site
(6) radiation therapy to first metastatic sites
Parameter
Finding
Points
age
<= 46 years
0
> 46 years
1
anemia
no
0
yes
2
N stage
N0
0
N1 or greater
2
bone metastasis free survival
<= 12 months
1
> 12 months
0
radiation to primary site
no
1
yes
0
radiation to first metastatic sites
no
1
yes
0
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 8
Total Score
Risk Group
5-Year Overall Survival
0 to 4
low
58%
5 to 8
high
25%
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