Brockelmann et al reported a prognostic score for patients with Hodgkin's lymphoma who have an autologous stem cell transplant (ASCT). The authors are from the University of Cologne, Hopital Le Bocage (Dijon), Copenhagen University Hospital, Memorial Sloan Kettering Cancer Center and Universite de Lille 2.
Patient selection: refractory or relapsed Hodgkin's lymphoma, with autologous stem cell transplant
Parameters:
(1) stage
(2) time to relapse (TTR) in months
(3) ECOG status
(4) bulky tumor (diameter >= 5 cm)
(5) response to salvage chemotherapy
Parameter
Finding
Points
stage
Stage I to III
0
Stage IV
1
time to relapse
<= 3 months
1
> 3 months
0
ECOG
0
0
>= 1
1
diameter of largest tumor
< 5 cm
0
>= 5 cm
1
response to salvage chemotherapy
yes
0
no
1
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 5
Total Score
5-Year PFS
0
77%
1
68%
2
57%
3, 4 or 5
35%
To read more or access our algorithms and calculators, please log in or register.