Bourdel-Marchasson et al reported a prognostic score for an older patient with cancer. This is based on components of the MNA (Mini Nutritional Assessment). The authors are from CHU Bordeaux, Bordeaux University and Institut Bergonie in France.
Patient selection: older adult with cancer
Outcome: 1-year mortality rate
Parameters:
(1) food intake over the past 3 months
(2) number of prescription drugs taken daily
(3) intake of protein-rich food
(4) calf circumference in centimeters
(5) organ of cancer origin
(6) metastases
(7) absolute lymphocyte count per microliter
|
Parameter
|
Finding
|
Points
|
|
food intake
|
no decrease
|
0
|
|
|
moderate decrease
|
7.1
|
|
|
severe decrease
|
13.4
|
|
number of prescription drugs
|
<= 3
|
0
|
|
|
> 3
|
4.8
|
|
intake of protein-rich foods
|
low
|
10
|
|
|
intermediate
|
5.2
|
|
|
high
|
0
|
|
calf circumference
|
< 31 cm
|
11.3
|
|
|
>= 31 cm
|
0
|
|
origin of cancer
|
non-small cell lung
|
18.6
|
|
|
colon
|
0
|
|
|
stomach
|
10.4
|
|
|
ovary
|
0.8
|
|
|
pancreas
|
15.1
|
|
|
cholangiocarcinoma
|
10.7
|
|
|
unknown
|
7
|
|
|
prostate
|
6.4
|
|
|
breast
|
6
|
|
|
urinary bladder
|
13.8
|
|
metastases
|
no
|
0
|
|
|
yes
|
8.8
|
|
absolute lymphocyte count
|
>= 1,500 per µL
|
0
|
|
|
< 1,500 per µL
|
8.4
|
total score =
= SUM(points for all 7 parameters)
Interpretation:
• minimum score: 0
• maximum score: 75.3
• Patients with a score <= 21 had a 1-year mortality of 19.5%.
• Patients with a score >= 31 had a 1-year mortality rate of 70%.
Performance:
• The area under the ROC curve is 0.79.
