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Prognostic Score of Barta et al for AIDS-Related Lymphoma: Total ARL-IPI

Description

Barta et al developed a prognostic score for a patient with AIDS-related lymphoma (ARL) based on the International Prognostic Index (IPI). This is based on data since the introduction of rituximab. The authors are from multiple hospitals in the United States and Europe.


 

Patient selection: malignant lymphoma in an HIV-positive patient

 

Outcome: 5-year overall survival

 

Parameters:

(1) age-adjusted IPI (from 0 to 3)

(2) HIV score (from 0 to 6)

(3) number of extranodal sites (ENS)

 

Number of Extranodal Sites

Points

0

0

1

1

2

2

>= 3

3

 

total ARL-IPI =

= (2 * (age-adjusted IPI) + (HIV subscore) + (points for ENS)

 

Interpretation:

• minimum score: 0

• maximum score: 15

• The higher the score the greater the risk.

 

Total Score

Risk Group

5-Year Overall Survival

0 to 6

low

78%

7 to 10

intermediate

60%

11 to 15

high

50%

 


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