Barta et al developed a prognostic score for a patient with AIDS-related malignant lymphoma. One component is a score for HIV-related parameters. The authors are from multiple hospitals in the United States and Europe.
Patient selection: HIV-positive patient with malignant lymphoma
Parameters:
(1) CD4 lymphocyte count
(2) HIV viral load in copies per mL
(3) history of AIDS
Parameter
Finding
Points
CD4 count
>= 500 per µL
0
200 to 499 per µL
1
50 to 199 per µL
2
< 50 per µL
3
viral load
>= 10,000 copies/mL
0
0.4 to 9,999 copies/mL
1
< 0.4 copies/mL
2
history of AIDS
no
0
yes
1
total subscore =
= SUM(points for the 3 parameters)
Interpretation:
• minimum subscore: 0
• maximum subscore: 6
• The higher the score the more advanced the HIV disease.
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