Shen et al reported a nomogram for predicting survival for a patient with CD5-positive diffuse large B-cell lymphoma. This can help to identify a patient who may benefit from more aggressive management or a novel therapy. The authors are from Xuzhou Medical University, Soochow University, Arhui Medical University, Shandong University and multiple affiliated hospitals.
Patient selection: CD5-positive diffuse large B-cell lymphoma
Parameters:
(1) red blood cell count in 10^12/L
(2) MYC expression in immunohistochemistry
(3) absolute neutrophil count
(4) hepatosplenomegaly
(5) International Prognostic Index (IPI)
(6) age in years
Parameters
Findings
Points
RBC Count
>= 3.62 * 10^12/L
0
< 3.62
100
MYC
negative
0
positive
98.7
neutrophil count
< 3.87 * 10^9/L
0
>= 3.87
81.2
hepatosplenomegaly
no
0
yes
85
IPI
low or low-intermediate
0
high-intermediate or high
95.9
age
< 74 years
0
>= 74 years
48.7
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 509.6
• The higher the score the worse the 5-year survival.
