Hsu et al reported a nomogram to predict the prognosis for a patient with hepatocellular carcinoma. The authors are from Taipei Veterans General Hospital, National Yang-Ming University (Taipei, Taiwan) and the University of Nevada.
Patient selection: hepatocellular carcinoma
Outcome: overall survival
Parameters:
(1) ECOG/WHO performance status (from 0 to 4)
(2) Child class (A, B, C)
(3) tumor burden
|
Tumor Burden |
Grade |
|
1 tumor < 2 cm in diameter, no vascular invasion |
0 |
|
Milan criteria (1 tumor 2 to 4.99 cm, 2 or 3 tumors all < 3 cm; no vascular invasion; no extrahepatic involvement) |
1 |
|
none of the other Grades |
2 |
|
vascular invasion, lymph node metastasis and/or distant metastases |
3 |
|
Parameter |
Finding |
Points |
|
performance status |
0 |
0 |
|
|
1 or 2 |
3 |
|
|
3 or 4 |
6.7 |
|
Child class |
A |
0 |
|
|
B |
5.2 |
|
|
C |
9 |
|
tumor burden |
Grade 0 |
0 |
|
|
Grade 1 |
1.2 |
|
|
Grade 2 |
3.7 |
|
|
Grade 3 |
10 |
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 25.7
• The higher the score the worse the overall survival.
percent 5-year survival =
= (0.1343 * ((points)^2)) - (6.771 * (points)) + 83.26
|
BCLC |
Point Range |
|
A |
1.2 to 6.3 |
|
B |
3.5 to 8.7 |
|
C |
2.9 to 18 |
|
D |
6.4 to 26 |
Specialty: Hematology Oncology, Surgery, general, Gastroenterology
