Gold et al developed a prognostic nomogram for a patient with a primary gastrointestinal tumor (GIST). These can help to identify a patient who may benefit from more aggressive management. The authors are from multiple hospitals in the United States and Spain.
Patient selection: primary GIST following complete surgical excision
Parameters:
(1) diameter in centimeters
(2) mitotic rate per 50 high power microscopic fields (hpf)
(3) site
|
Diameter |
Points |
|
< 15 cm |
(-0.198 * ((diameter)^2)) + (7.826 * (points)) - 0.07 |
|
>= 15 cm |
49.73 + (1.007 * (diameter)) |
where:
• The diameter in the nomogram goes to 50 cm or 0.5 meter.
|
Parameter |
Finding |
Points |
|
mitotic rate |
0 to 4 per 50 hpf |
0 |
|
|
>= 5 per 50 hpf |
81 |
|
location |
stomach |
0 |
|
|
colon or rectum |
6 |
|
|
small bowel |
39 |
|
|
other |
0 |
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 220
• The higher the score the worse the prognosis.
|
Total Score |
Percent with 5-Year Recurrence Free Survival |
|
< 33 |
> 90% |
|
33 to 83 |
(-0.007134 * ((points)^2)) + (0.227 * (points)) + 90.38 |
|
83 to 130 |
149.6 - (1.081 * (points)) |
|
> 130 |
< 10% |
Specialty: Hematology Oncology, Surgery, general, Gastroenterology
ICD-10: ,
