Cao et al reported a prognostic nomogram for a patient with multiple system atrophy (MSA). This can help to identify a patient who may require more aggressive management. The authors are from West China Hospital and Sichuan University in Chengdu, China.
Patient selection: multiple system atrophy
Parameters:
(1) diagnostic delay in years
(2) total Unified Multiple System Atrophy Rating Scale (UMSARS) score
(3) orthostatic hypotension
(4) autonomic onset (vs motor)
Parameter
Finding
Points
diagnostic delay
< 1.05 years
100
1.05 to 3.06
66.6
3.07 to 4.05
33.3
> 4.05 years
0
total UMSARS
< 33
0
34 to 42
29.8
43 to 53
59.5
> 53
89.6
orthostatic hypotension
no
0
yes
40.1
autonomic onset
no
0
yes
35.6
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 265.3
• The higher the score the worse the long-term survival.
