Zhu et al reported a prognostic model for a patient with mantle cell lymphoma. This can help to identify a patient who may benefit from more aggressive management. The authors are from Soochow University in Changzhou, China.
Patient selection: mantle cell lymphoma
Presentation of model: nomogram
Parameters:
(1) Ki-67 in percent
(2) WBC count in 10^9/L
(3) age in years
(4) ECOG performance status
(5) ratio of serum LDH to upper limit of normal
Parameter
Finding
Points
Ki-67
<30%
0
>= 30%
98
WBC
< 6.7 * 10^9/L
0
6.7 to 9.99
9.6
10 to 14.99
19.2
>= 15
29.6
age
< 50
0
50 to 59
13.8
60 to 69
27.5
>= 70
41.5
ECOG
0 or 1
0
2 to 4
100
LDH to ULN ratio
< 0.67
0
0.67 to 0.99
29
1.00 to 1.49
58.8
>= 1.5
88
total score =
= SUM(points for all 5 parameters)
Interpretation:
• minimum score: 0
• maximum score: 357.1
• The higher the score the worse the overall survival.
