Zhao et al reported a prognostic model for patients with diffuse large B-cell lymphoma. This can help to identify a patient who may benefit from more aggressive management. The authors are from Tianjin Medical University and the National Clinical Research Center for Cancer in Tianjin, China.
Parameters: diffuse large B-cell lymphoma
Parameters:
(1) platelet to lymphocyte ratio (PLR)
(2) IPI (from 0 to 5) or age-adjusted IPI (R-IPI of Sehn et al, from 0 to 5)
(3) serum beta-2-microglobulin (reference range -/97 to 2.64 mg/L)
PLR
IPI (R-IPI)
beta-2-microglobulin
Risk Group
< 170
0 or 1 (R-IPI 0)
normal
low
>= 170
>= 4 (R-IPI 3)
high
high
Other patterns were intermediate risk.
Risk Group
5-Year Overall Survival
low
86%
intermediate
54%
high
21%
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