Wilcox et al evaluated the prognostic significance of the absolute monocyte and lymphocyte counts in patients with diffuse large B-cell lymphoma (DLBCL). A model using both is comparable to the IPI for risk stratification. The authors are from the Mayo Clinic in Rochester.
Patient selection: diffuse large B-cell lymphoma
Parameters:
(1) absolute monocyte count per microliter at the time of diagnosis
(2) absolute lymphocyte count per microliter at the time of diagnosis
Absolute Monocyte Count
Absolute Lymphocyte Count
Risk Group
< 630
>1,000
low
>= 630
> 1,000
intermediate
< 630
<= 1,000
intermediate
>= 630
<= 1,000
high
Risk Group
5-Year Progression Free Survival
low
83%
intermediate
59%
high
30%
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