Sheng et al reported a prognostic score for a patient with the hepatorenal syndrome. This can help to identify a patient who may require more aggressive management. The authors are from Zhejiang University and National Clinical Research Center for Infectious Diseases in China.
Patient: adult (age > 18 years) with hepatorenal syndrome
GIMNS is an acronym for gender, INR, MCHC, neutrophils, stage)
Parameters:
(1) sex/gender
(2) percent neutrophils (from 0 to 100)
(3) MCHC in g/L
(4) INR
(5) stage based on number of non-renal organ failures
Parameters
Finding
Points
sex
male
-1.412
female
0
percent neutrophils
0.053 * (percent)
MCHC
0.014 * (MCHC)
INR
2.073 * LN(INR)
stage
0 or 1 non-renal organ fail
0
>= 2 non-renal organ fail
1.231
score =
= SUM(points for all of the parameters) - 9.217
GIMNS Score
28-day Mortality
< 0
30%
0 to 1
57%
1 to 2
74%
>= 2
100%
Performance:
• The area under the ROC curve is 0.83.
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