Prognostic Model of Price et al for Hematopoietic Stem Cell or Bone Marrow Transplant Patients Admitted to the Intensive Care Unit

Description

Patients with a peripheral blood hematopoietic stem cell (PBSCT) or bone marrow transplant (BMT) tend to have a poor prognosis if they are admitted to the intensive care unit (ICU). Price et al developed a prognostic model for predicting mortality in these patients. This can help determine if intubation or other intervention is likely to benefit the patient. The authors are from MD Anderson Cancer Center in Houston.

Parameters identified in multiple logistic regression:

(1) intubation

(2) type of transplant

(3) infection

(4) respiratory rate

(5) days since transplant

(6) GI bleeding

(7) total bilirubin

(8) heart rate

Parameter	Finding	Points
intubated	no	0
	yes	1
type of transplant	non-allogenic	0
	allogenic	1
infection	absent	0
	probable	1
respiratory rate in breaths/minute		(respiratory rate)
days since transplant		(days) /100
GI bleeding	absent	0
	present	1
total bilirubin in mg/dL		LN(bilirubin)
heart rate in beats/minute		(heart rate)

X =

= (2.516 * (points for intubation)) + (1.525 * (points for transplant type)) + (4.412 * (points for infection)) + (0.088 * (points for respiratory rate)) + (0.635 * (points for days)) - (0.031 * ((points for days)^2)) + (3.177 * (points for GI bleeding)) + (0.884 * (points for bilirubin)) + (0.292 * (points for heart rate)) - (0.0013 * ((points for heart rate)^2)) – 25.501

probability of mortality =

= EXP(X) / (1 + EXP(X))

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Description

Specialty

ICD-10