Low et al developed a prognostic model for patients with Hodgkin's disease. This can help identify patients who may benefit from more aggressive management. The authors are from Weston Park Hospital, University of Sheffield, the British National Lymphoma Investigation and CRC and UCL Cancer Trails Centre in England.
Parameters:
(1) age of the patient in years
(2) serum albumin
(3) absolute lymphocyte count
Parameter |
Finding |
Points |
age of the patient |
< 45 years of age |
0 |
|
>= 45 years of age |
1 |
serum albumin |
> 35 g/L |
0 |
|
<= 35 g/L |
1 |
absolute lymphocyte count |
> 1.5 * 10^9/L |
0 |
|
<= 1.5 * 10^9/L |
1 |
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
• The higher the score the worse the prognosis.
Total Score |
Risk Group |
10 Year Survival |
20 Year Survival |
0 |
A |
85% |
75% |
1 |
B |
72% |
57% |
2 |
C |
56% |
40% |
3 |
D |
34% |
20% |
Specialty: Hematology Oncology