Lee et al used the Geriatric Nutritional Risk Index (GNRI) and Charlson Comorbidity Index (CCI) to predict survival for an older adult with diffuse large B-cell lymphoma (DLBCL). The authors are from multiple institutions in Japan.
Patient selection: >= 65 years, with diffuse large B-cell lymphoma
Parameters:
(1) Geriatric Nutritional Risk Index (GNRI) of Bouillanne et al
(2) Charlson Comorbidity Index (CCI)
Parameter
Finding
Risk Group
GNRI
> 98
no
92 to 98
mild
82 to 91.99
moderate
< 82
high
Charlson comorbidity index
0
low
1 or 2
medium
3 or 4
high
>= 5
very high
According to page 102, second column:
(1) mortality risk increased significantly when GNRI < 92 (moderate and high)
(2) relative hazard increased when the CCI was over 3 or 4 (very high risk)
GNRI
CCI
HR Overall Survival
10 Year Overall Survival
no risk
no risk
1
73%
no risk
at risk
2.5
40%
at risk
no risk
3.4
40%
at risk
at risk
6.8
15%
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