Kanemasa et al reported a simple prognostic index for patients with diffuse large B-cell lymphoma (DLBCL). The authors are from Metropolitan Cancer and Infectious Disease Center Komagome Hospital in Tokyo.
Patient selection: diffuse large B-cell lymphoma
Parameters:
(1) age in years
(2) Ann Arbor stage
(3) serum beta-2 microglobulin in mg/L
(4) ECOG performance status
Parameter
Finding
Points
age in years
<= 60 years
0
> 60 years
1
Ann Arbor stage
I or II
0
III or IV
1
serum beta-2 microglobuin
< 3.2 mg/L
0
>= 3.2 mg/L
1
ECOG performance status
0 or 1
0
2 to 4
1
score =
= SUM(points for all 4 parameters)
Interpretation:
• minimum score: 0
• maximum score: 4
• The higher the score the worse the prognosis,
Score
Risk Group
3-Year Overall Survival
0
low
100%
1 or 2
low-intermediate
87%
3
high-intermediate
57%
4
high
23%
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