Huang et al reported a prognostic model for patients with angioimmunoblastic T-cell lymphoma (AITL). This can help to identify a patient who may require more aggressive management. The authors are from Hebei Medical University in China.
Patient selection: angioimmunoblastic T-cell lymphoma
Parameters:
(1) age in years
(2) serum albumin in g/L
(3) tumor Ki-67 rate in percent
(4) Coombs (antiglobulin) test
(5) Ann Arbor stage
Parameter
Finding
Points
age
<= 60 years
0
> 60 years
2
serum albumin
>= 30 g/L
< 30 g/L
1.5
tumor Ki-67
< 70%
>= 70%
1
Coombs test
negative
positive
Ann Arbor stage
I or II
III or IV
total score =
= SUM(points for all of the parameters)
Interpretation:
• minimum score: 0
• maximum score: 7.5
• The higher the score the worse the prognosis.
Total Score
Risk Group
3-Year Overall Survival
0 to 2.5
low
86%
3 or 4
intermediate
38%
4.5 to 7.5
high
10%
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Specialty: Hematology Oncology
