Hong et al reported a prognostic model for a patient with angioimmunoblastic T-cell lymphoma (AITL). This can help to identify a patient who may benefit from more aggressive management. The authors are from the State Key Laboratory of Oncology in Southern China and Collaborative Innovation Center of Cancer Medicine in Guangzhou, China.
Patient selection: AITL
Outcome: 5-year overall survival
Parameters from multivariate analysis:
(1) bone marrow involvement
(2) number of extranodal sites
(3) ECOG performance status
Parameter
Finding
Points
bone marrow involvement
no
0
yes
1
number of extranodal sites
0 or 1
0
2 or more
1
ECOG performance
0 or 1
0
2 to 4
1
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
• The higher the score the worse the prognosis.
Total Score
Risk Group
5-Year Overall Survival
0
low
87%
1
intermediate
46%
2 or 3
high
16%
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