Description

Hernandez-Boluda et al reported a prognostic model for a patient with myelofibrosis who undergoes an allogeneic hematopoietic cell transplant. The authors are from multiple institutions in Spain.


Patient selection: myelofibrosis

 

Parameters:

(1) HCT-CI (hematopoietic cell transplantation-specific comorbidity index)

(2) donor

(3) use of PT-Cy (post-transplant cyclophosphamide)

 

Parameter

Finding

Points

HCT-CI

< 3

0

 

>= 3

1

donor

HLA-mismatched unrelated donor or cord blood

1

 

other

0

use of PT-Cy

no

0

 

yes

-1

 

total score =

= SUM(points for all of the parameters)

 

Interpretation:

• minimum score: -1

• maximum score: 2

 

Score

Risk Group

5-Year Overall Survival

-1

low

79%

0

intermediate

55%

1 or 2

high

32%

 


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