Chavda et al reported a simple prognostic model for a patient with myeloma who has relapsed following an upfront autologous stem cell transplant (HSCT). The authors are from University College London.
Patient selection: myeloma treated with upfront autologous stem cell transplant
Parameters:
(1) number of months between autologous stem cell transplant and relapse (progression-free survival)
(2) International Staging System (ISS) stage at relapse
Parameter
Finding
Points
number of months
<= 12 months
1
> 12 months
0
ISS stage
1
0
2 or 3
1
score =
= SUM(points for the 2 parameters)
Interpretation:
• minimum score: 0
• maximum score: 2
Score
Median Post-Relapse Survival
0
65 months
1
34 months
2
10 months
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