Arcaini et al developed a prognostic model for patients with splenic marginal zone lymphoma. This can help identify patients who may benefit from more aggressive management. The authors are members of the Intergruppo Italiano Linfomi representing multiple oncology centers in Italy.
Parameters:
(1) hemoglobin in g/dL
(2) serum LDH
(3) serum albumin
Parameter
Finding
Points
hemoglobin
>= 12.0 g/dL
0
< 12.0 g/dL
1
serum LDH
<= upper limit of normal
0
> upper limit of normal
1
serum albumin
>= 3.5 g/dL
0
< 3.5 g/dL
1
total score =
= SUM(points for all 3 parameters)
Interpretation:
• minimum score: 0
• maximum score: 3
• The higher the score the worse the prognosis.
Total Score
Risk Group
5 Year Cause Specific Survival
0
low
88%
1
intermediate
73%
2 or 3
high
50%
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